GPCR-GRAPA-LIB-a refined library of hidden Markov Models for annotating GPCRs
نویسندگان
چکیده
GPCR-GRAPA-LIB is a library of HMMs describing G protein coupled receptor families. These families are initially defined by class of receptor ligand, with divergent families divided into subfamilies using phylogenic analysis and knowledge of GPCR function. Protein sequences are applied to the models with the GRAPA curve-based selection criteria. RefSeq sequences for Homo sapiens, Drosophila melanogaster, and Caenorhabditis elegans have been annotated using this approach.
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ورودعنوان ژورنال:
- Bioinformatics
دوره 19 5 شماره
صفحات -
تاریخ انتشار 2003